Document Type : Blackboard
Authors
1 department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran
2 Health Management and Economics Research Center, Iran University of Medical Science, Tehran, Iran.
Abstract
The radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. Responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. These changes are confirmed by results of some In-Vivo studies. Most well-known important factors affecting radiation-induced bystander effect include free radicals, immune system factors, expression changes of some genes involved in inflammation pathway and epigenetic factors.
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