Document Type : Original Research
Authors
1 Ph.D of Medical Physics. Assistant professor, Department of Medical Physics and Radiotherapy, Arak university of Medical Sciences and Khansari hospital, Arak, Iran
2 Ph.D of Physics. Associate professor, Department of Physics, Arak University, Arak, Iran
3 Ms.c of Physics, Department of Physics, Arak University, Arak, Iran
Abstract
Background: Considering that some vital organs exist in the head and neck region, the treatment of tumors in this area is a crucial task. The existence of air cavities, namely sinuses, disrupt the radiotherapy dose distribution. The study aims to analyze the effect of maxillary, frontal, ethmoid and sphenoid sinuses on radiotherapy dose distribution by Monte Carlo method.
Material and Methods: In order to analyze the effect of the cavities on dose distribution, the maxillary, frontal, ethmoid and sphenoid sinus cavities were simulated with (3×3.2×2) cm3, (2×2×3.2) cm3, (1×1×1.2) cm3 and (1×1×2) cm3 dimensions.
Results: In the analysis of the dose distribution caused by cavities, some parameters were observed, including: inhomogeneity of dose distribution in the cavities, inhomogeneity of dose on the edges of the air cavities and dispersion of the radiations after the air cavity. The amount of the dose in various situations showed differences: before the cavity a 0.64% and a 2.76% decrease, a 12.06% and a 17.17% decrease in the air zone, and a 2.25% and a 5.9% increase after the cavity.
Conclusion: The results indicate that a drop in dose before the air cavities and in the air zone occurs due to the lack of scattered radiation. Furthermore, the rise in dose was due to the passage of more radiation from the air cavity and dose deposition after the air cavity. The changes in dose distribution are dependent on the cavity size and depth. As a result, this has to be noted in the treatment planning and MU calculations of the patient.
Keywords
- Joshi CP, Darko J, Vidyasagar P, Schreiner LJ. Dosimetry of interface region near closed air cavities for Co-60, 6 MV and 15 MV photon beams using Monte Carlo simulations. Journal of Medical Physics/Association of Medical Physicists of India. 2010;35:73.doi: 10.4103/0971-6203.62197.
- Miura H, Masai N, Yamada K, Sasaki J, Oh R-J, Shiomi H, et al. Evaluation and commissioning of commercial Monte Carlo dose algorithm for air cavity. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology. 2014;3:9.doi: 10.4236/ijmpcero.2014.31002.
- Osei EK, Darko J, Mosseri A, Jezioranski J. EGSNRC Monte Carlo study of the effect of photon energy and field margin in phantoms simulating small lung lesions. Med Phys. 2003;30:2706-14. doi: 10.1118/1.1607551. PubMed PMID: 14596309.
- Chow JC, Grigorov GN. Dosimetry of a small air cavity for clinical electron beams: A Monte Carlo study. Med Dosim. 2010;35:92-100. doi: 10.1016/j.meddos.2009.03.004. PubMed PMID: 19931020.
- Li XA, Yu C, Holmes T. A systematic evaluation of air cavity dose perturbation in megavoltage x-ray beams. Med Phys. 2000;27:1011-7. doi: 10.1118/1.598966. PubMed PMID: 10841404.
- Niroomand-Rad A, Harter KW, Thobejane S, Bertrand K. Air cavity effects on the radiation dose to the larynx using Co-60, 6 MV, and 10 MV photon beams. International Journal of Radiation Oncology* Biology* Physics. 1994;29:1139-46.doi: 10.1016/0360-3016(94)90411-1.
- Paelinck L, Reynaert N, Thierens H, De Wagter C, De Neve W. The value of radiochromic film dosimetry around air cavities: experimental results and Monte Carlo simulations. Phys Med Biol. 2003;48:1895-905.doi: 10.1088/0031-9155/48/13/303.PubMed PMID: 12884923.
- Shortt K, Ross C, Bielajew A, Rogers D. Electron beam dose distributions near standard inhomogeneities. Phys Med Biol. 1986;31:235.doi: 10.1088/0031-9155/31/3/003.
- Zarza-Moreno M, Carreira P, Madureira L, Miras Del Rio H, Salguero FJ, Leal A, et al. Dosimetric effect by shallow air cavities in high energy electron beams. Phys Med. 2014;30:234-41. doi: 10.1016/j.ejmp.2013.07.125. PubMed PMID: 23920079.
- Shahbazi D, Changizi B, Jomehzadeh A. The effect of contrast media on treatment planning and dose calculation in radiation therapy of pelvis cancers. J Med Isfahan School. 2017;34:1389-94.
- Epp ER, Lougheed MN, Mc KJ. Ionization build-up in upper respiratory air passages during teletherapy with cobalt 60 radiation. Br J Radiol. 1958;31:361-7. doi: 10.1259/0007-1285-31-367-361. PubMed PMID: 13560735.
- Petoukhova AL, Terhaard CH, Welleweerd H. Does 4 MV perform better compared to 6 MV in the presence of air cavities in the head and neck region? Radiother Oncol. 2006;79:203-7. doi: 10.1016/j.radonc.2006.04.002. PubMed PMID: 16698100.
- ehrens C. Dose build-up behind air cavities for Co-60, 4, 6 and 8 MV. Measurements and Monte Carlo simulations. Phys Med Biol. 2006;51:5937.doi: 10.1088/0031-9155/51/22/015.
- Beach J, Mendiondo M, Mendiondo O. A comparison of air-cavity inhomogeneity effects for cobalt-60, 6-, and 10-MV x-ray beams. Med Phys. 1987;14:140-4.doi: 10.1118/1.596101.
- Kan WK, Wu PM, Leung HT, Lo TC, Chung CW, Kwong DL, et al. The effect of the nasopharyngeal air cavity on x-ray interface doses. Phys Med Biol. 1998;43:529-37. PubMed PMID: 9533132.
- Khan FM. The Physics of Radiation Therapy. Philadelphia; Lippincott, Williams & Wilkins. 2010.
- Klein EE, Chin LM, Rice RK, Mijnheer BJ. The influence of air cavities on interface doses for photon beams. Int J Radiat Oncol Biol Phys. 1993;27:419-27.doi: 10.1016/0360-3016(93)90255-x.PubMed PMID: 8407418.