Document Type: Original Research

Authors

1 MSc, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences(TUMS), Tehran, Iran

2 PhD, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences(TUMS), Tehran, Iran

3 PhD, Medical Pharmaceutical Sciences Research Center (MPRC), The institute of Pharmaceutical Sciences, Tehran University of Medical Sciences, Tehran, Iran

4 PhD, Department of Medical Physics and Biomedical Engineering, School of Medicine, Kermanshah University of Medical Sciences (KUMS), Kermanshah, Iran

5 MD, Department of Radiology, School of Medicine, Tehran University of Medical Sciences(TUMS), Tehran, Iran

6 MD, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences(TUMS), Tehran, Iran

7 MSc Student, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences(TUMS), Tehran, Iran

Abstract

Background: fNIRS is a useful tool designed to record the changes in the density of blood’s oxygenated hemoglobin (oxyHb) and deoxygenated hemoglobin (deoxyHb) molecules during brain activity. This method has made it possible to evaluate the hemodynamic changes of the brain during neuronal activity in a completely non-aggressive manner.
Objective: The present study has been designed in order to investigate and evaluate the brain cortex activities during imagining of the execution of wrist motor tasks by comparing fMRI and fNIRS imaging methods.
Material and Methods: This novel observational Optical Imaging study aims to investigate the brain motor cortex activity during imagining of the right wrist motor tasks in vertical and horizontal directions. In order to perform the study, ten healthy young right-handed volunteers were asked to think about right-hand movements in different directions according to the designed movement patterns. The required data were collected in two wavelengths, including 845 and 763 nanometer using a 48 channeled fNIRS machine.
Results: Analysis of the obtained data showed the brain activity patterns during imagining of the execution of a movement are formed in various points of the motor cortex in terms of location. Moreover, depending on the direction of the movement, activity plans have distinguishable patterns.The results showed contralateral M1 were mainly activated during imagining of the motor cortex (p <0.05).
Conclusion: The results of our study showed that in brain imaging, its possible to distinguish between patterns of activities during wrist motion in different directions using the recorded signals obtained through near infrared Spectroscopy. Findings of this study can be useful in further studies related to movement control and BCI.

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