Document Type : Original Article

Authors

1 School of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi, UP, India

2 Department of Radiotherapy and Radiation Medicine, Institute of Medical Science (BHU), Varanasi, UP, India

Abstract

Introduction: This study investigates basic dosimetric properties of unflattened 6 MV photon beam shaped by multileaf collimator and compares them with those of flattened beams.
Materials and Methods: Monte Carlo simulation model using BEAM code was developed for a 6MV photon beam based on Varian Clinic 600 unique performance linac operated with and without a flattening filter in beam line. Dosimetric features including lateral profiles, central axis depth dose, photon and electron spectra were calculated for flattened and unflattened cases, separately.
Results: An increase in absolute depth dose with a factor of more than 2.4 was observed for unflattened beam which was dependent on depth. PDDs values were found to be lower for unflattened beam for all field sizes. Significant decrease in calculated mlc leakage was observed when the flattening filter was removed from the beam line. The total scatter factor, SCP was found to show less variation with field sizes for unflattened beam indicating a decrease in head scatter. The beam profiles for unflattened case are found to have lower relative dose value in comparison with flattened beam near the field edge, and it falls off faster with distance.
Conclusion: Our study showed that increase in the dose rate and lower peripheral dose could be considered as realistic advantages for unflattened 6MV photon beams.

Keywords

  1. Fu W, Dai J, Hu Y, Han D, Song Y. Delivery time comparison for intensity-modulated radiation therapy with/without flattening filter: a planning study. Phys Med Biol. 2004;49:1535-47. doi.org/10.1088/0031-9155/49/8/011. PubMed PMID: 15152690.
  2. Gillies BA, O’Brien PF, McVittie R, McParland C, Easton H. Engineering modifications for dynamic stereotactically assisted radiotherapy. Med Phys. 1993;20:1491-5. doi.org/10.1118/1.597112. PubMed PMID: 8289733.
  3. O’Brien PF, Gillies BA, Schwartz M, Young C, Davey P. Radiosurgery with unflattened 6-MV photon beams. Med Phys. 1991;18:519-21. doi.org/10.1118/1.596656. PubMed PMID: 1908047.
  4. Jeraj R, Mackie TR, Balog J, Olivera G, Pearson D, Kapatoes J, et al. Radiation characteristics of helical tomotherapy. Med Phys. 2004;31:396-404. doi.org/10.1118/1.1639148. PubMed PMID: 15000626.
  5. Verhaegen F, Seuntjens J. Monte Carlo modelling of external radiotherapy photon beams. Phys Med Biol. 2003;48:R107-64. doi.org/10.1088/0031-9155/48/21/R01. PubMed PMID: 14653555.
  6. Sheikh-Bagheri D, Rogers DW. Monte Carlo calculation of nine megavoltage photon beam spectra using the BEAM code. Med Phys. 2002;29:391-402. doi.org/10.1118/1.1445413. PubMed PMID: 11930914.
  7. Mesbahi A, Reilly AJ, Thwaites DI. Development and commissioning of a Monte Carlo photon beam model for Varian Clinac 2100EX linear accelerator. Appl Radiat Isot. 2006;64:656-62. doi.org/10.1016/j.apradiso.2005.12.012. PubMed PMID: 16455264.
  8. Lee PC. Monte Carlo simulations of the differential beam hardening effect of a flattening filter on a therapeutic x-ray beam. Med Phys. 1997;24:1485-9. doi.org/10.1118/1.598037. PubMed PMID: 9304577.
  9. Vassiliev ON, Titt U, Kry SF, Ponisch F, Gillin MT, Mohan R. Monte Carlo study of photon fields from a flattening filter-free clinical accelerator. Med Phys. 2006;33:820-7. doi.org/10.1118/1.2174720. PubMed PMID: 16696457.
  10. Titt U, Vassiliev ON, Ponisch F, Dong L, Liu H, Mohan R. A flattening filter free photon treatment concept evaluation with Monte Carlo. Med Phys. 2006;33:1595-602. doi.org/10.1118/1.2198327. PubMed PMID: 16872067.
  11. Ponisch F, Titt U, Vassiliev ON, Kry SF, Mohan R. Properties of unflattened photon beams shaped by a multileaf collimator. Med Phys. 2006;33:1738-46. doi.org/10.1118/1.2201149. PubMed PMID: 16872081.
  12. Rogers DW, Faddegon BA, Ding GX, Ma CM, We J, Mackie TR. BEAM: a Monte Carlo code to simulate radiotherapy treatment units. Med Phys. 1995;22:503-24. doi.org/10.1118/1.597552. PubMed PMID: 7643786.
  13. Rogers D, Ma C, Walters B, Ding G, Sheikh-Bagheri D, Zhang G. BEAMnrc Users Manual National Research Council of Canada. NRCC Report PIRS-0509 (A) revK. 2002.
  14. Kawrakow I, Walters BR. Efficient photon beam dose calculations using DOSXYZnrc with BEAMnrc. Med Phys. 2006;33:3046-56. doi.org/10.1118/1.2219778. PubMed PMID: 16964882.
  15. Walters B, Kawrakow I, Rogers D. DOSXYZnrc users manual. NRC Report PIRS. 2005;794.
  16. Ma C, Rogers D. BEAMDP as a General Purpose Utility National Research Council of Canada Report no. PIRS-0509 (E)(NRCC, Ottawa, Canada). 1998.