Document Type : Original Research
Authors
Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
Objective: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for 60Co, 137Cs, 192Ir and 103Pd brachytherapy sources by Monte Carlo simulation.
Methods: In this study, 60Co (model Co0.A86), 137Cs (model 6520-67), 192Ir (model BEBIG) and 103Pd (model OptiSeed) brachytherapy sources were simulated using MCNPX Monte Carlo code. To simulate the sources, the exact geometric characterization of each source was defined in Monte Carlo input programs. Dosimetric parameters including air kerma strength, dose rate constant, radial dose function and anisotropy function were calculated for each source. Each input program was run with sufficient number of particle histories. The maximum type A statistical uncertainty in the simulation of the 60Co, 137Cs, 192Ir and 103Pd sources, were equal to 4%, 4%, 3.19% and 6.50%, respectively.
Results: The results for dosimetry parameters of dose rate constant, radial dose function and anisotropy function for the 60Co, 137Cs, 192Ir and 103Pd sources in this study demonstrated good agreement with other studies.
Conclusion: Based on the good agreement between the results of this study and other studies, the TG-43 results for Co0.A86 60Co, 67-65200 137Cs, BEBIG 192Ir and OptiSeed 103Pd sources are validated and can be used as input data in treatment planning systems (TPSs) and to validate the TPS calculations.
Keywords
- Suntharalingam N, Podgorsak EB, Tolli H. Brachytherapy: physical and clinical aspects. Podgorsak EB. Radiation Oncology Physics: a handbook for teachers and students. Vienna: International Atomic Energy Agency; 2005. p. 451-484.
- Enger SA, Lundqvist H, D’Amours M, Beaulieu L. Exploring 57Co as a new isotope for brachytherapy applications. Med Phys. 2012;39:2342-5. doi.org/10.1118/1.3700171. PubMed PMID: 22559604.
- Oliveira SM, Teixeira NJ, Fernandes L, Teles P, Vaz P. Dosimetric effect of tissue heterogeneity for 125I prostate implants. Rep Pract Oncol Radiother. 2014;19:392-8. doi.org/10.1016/j.rpor.2014.03.004. PubMed PMID: 25337412. PubMed PMCID: 4201780.
- Williamson JF, Li Z. Monte Carlo aided dosimetry of the microselectron pulsed and high dose-rate 192Ir sources. Med Phys. 1995;22:809-19. doi.org/10.1118/1.597483. PubMed PMID: 7565372.
- Rivard MJ, Butler WM, DeWerd LA, Huq MS, Ibbott GS, Meigooni AS, et al. Supplement to the 2004 update of the AAPM Task Group No. 43 Report. Med Phys. 2007;34:2187-205. doi.org/10.1118/1.2736790. PubMed PMID: 17654921.
- Granero D, Perez-Calatayud J, Ballester F. Monte Carlo calculation of the TG-43 dosimetric parameters of a new BEBIG Ir-192 HDR source. Radiother Oncol. 2005;76:79-85. doi.org/10.1016/j.radonc.2005.06.016. PubMed PMID: 16019091.
- Mowlavi A, Binesh A, Moslehitabar H. Dose distribution and dosimetry parameters calculation of MED3633 palladium-103 source in water phantom using MCNP. Iran J Radiat Res. 2006;4:15-9.
- Pérez-Calatayud J, Granero D, Ballester F, Puchades V, Casal E. Monte Carlo dosimetric characterization of the Cs-137 selectron/LDR source: Evaluation of applicator attenuation and superposition approximation effects. Medical physics. 2004;31:493-9. doi.org/10.1118/1.1644640. PubMed PMID: 15070245.
- Granero D, Perez-Calatayud J, Ballester F. Technical note: Dosimetric study of a new 60Co source used in brachytherapy. Med Phys. 2007;34(9):3485-8.
- Meigooni AS, Wright C, Koona RA, Awan SB, Granero D, Perez-Calatayud J, et al. TG-43 U1 based dosimetric characterization of model 67-6520 Cs-137 brachytherapy source. Med Phys. 2009;36:4711-9. doi.org/10.1118/1.3224462. PubMed PMID: 19928102.
- Bernard S, Vynckier S. Dosimetric study of a new polymer encapsulated palladium-103 seed. Phys Med Biol. 2005;50:1493-504. doi.org/10.1088/0031-9155/50/7/012. PubMed PMID: 15798339.
- Perez-Calatayud J, Ballester F, Das RK, Dewerd LA, Ibbott GS, Meigooni AS, et al. Dose calculation for photon-emitting brachytherapy sources with average energy higher than 50 keV: report of the AAPM and ESTRO. Med Phys. 2012;39:2904-29. doi.org/10.1118/1.3703892. PubMed PMID: 22559663.
- Li Z, Palta JR, Fan JJ. Monte Carlo calculations and experimental measurements of dosimetry parameters of a new 103Pd source. Med Phys. 2000;27:1108-12. doi.org/10.1118/1.598975. PubMed PMID: 10841416.