Document Type : Short Communication
Authors
- Mehdi Faraz 1
- Samaneh Nematollahi 2
- Sedigheh Tahmasebi 3
- Seyed Mohammad Javad Mortazavi 4, 5
- Seyed Alireza Mortazavi 6
- James S Welsh 7, 8
- Joseph John Bevelacqua 9
1 Department of Computing, University of Turku, 20500, Turku, Finland
2 Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran
3 Breast Cancer Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
4 Department of Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
5 Ionizing and Non-Ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran
6 MVLS College, The University of Glasgow, Glasgow, Scotland, UK
7 Department of Radiation Oncology, Edward Hines Jr VA Hospital, Hines, IL, United States
8 Department of Radiation Oncology, Loyola University Stritch School of Medicine, Chicago, United States
9 Bevelacqua Resources, Richland, WA, United States
Abstract
The relationship between breast size and breast cancer risk is complex and not fully understood. This study investigates how breast size, categorized by cup size, correlates with age-standardized rates (ASR) of breast cancer incidence.
Data were collected from two sources: breast cancer incidence rates from the Global Cancer Observatory (GCO) and breast size data from “Data Pandas,” an open-access database. This allowed for a cross-country analysis of breast cancer incidence and breast size characteristics. Descriptive statistics indicated that ASR increased with larger cup sizes, ranging from 34.72 (AA) to 90.17 (C). An ANOVA test revealed significant differences in mean ASR among cup size groups (F=14.416, P<0.001), with Bonferroni comparisons showing distinct clusters: smaller sizes (AA, AA-A, A) differed significantly from larger sizes (A-B, B, B-C, C).The largest mean ASR difference was between groups A and C (-42.93, P=0.001), highlighting higher ASR in larger cup sizes. This suggests a significant association between breast cup size and breast cancer ASR, potentially linked to physiological or hormonal factors.Despite limitations, these findings prompt further investigation. The next phase will focus on breast cancer patients, addressing relevant risk factors for a more comprehensive understanding of the associations observed.
Keywords
)