Journal of Biomedical Physics and Engineering

Dosimetric Analysis of BEBIG 60Co and Flexisource 192Ir HDR Brachytherapy Sources using Geant4 Simulation

Articles in Press

Document Type : Original Research

Authors

Naser Hussein Judran Alrikabi 1, 2
Hassan Ali Nedaei 1, 2
Nooshin Banaee 3

1 Department of Medical Physics & Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran

2 Radiation Oncology Research Centre, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran

3 Medical Radiation Research Center, Central Tehran Branch, Islamic Azad University, Tehran, Iran

10.31661/jbpe.v0i0.2412-1862
Abstract
Background: This study validates the precision of dosimetric constraints for the BEBIG 60Co and Flexisource 192Ir Brachytherapy Sources using the Geant4 Monte Carlo code, commonly applied in clinical brachytherapy.
Objective: The current study aimed to assess the effects of tissue heterogeneities on dosimetry by evaluating key parameters for the BEBIG 60Co and Flexisource 192Ir Brachytherapy Sources.
Material and Methods: In this simulation study, the geometries of the BEBIG 60Co and 192Ir Flexi-sources were modeled within a water sphere. Key dosimetric parameters, including air kerma strength (SkS), dose rate constant (λ), radial dose function (g(r)), and anisotropy function (F(r,θ)) were calculated according to TG-43 and ESTRO standards.
Results: The dose rate constants for BEBIG 60Co and 192Ir Flexi-sources were 1.079 cGy/h ±0.008 and 1.099 cGy/h ±0.01, respectively, with deviations of 0.73% and 0.91% from reference values. The radial dose function showed a maximum deviation of less than 2% at 15 cm for both sources, indicating strong agreement with the reference data. 
Conclusion: Geant4 Monte Carlo simulations provide precise validation of BEBIG 60Co and 192Ir Flexi-sources. The findings suggest that 60Co offers a dosimetric advantage by reducing exposure to nearby organs while effectively reaching distant tissues, potentially enhancing treatment precision and safety in clinical brachytherapy.

Keywords

Brachytherapy
Monte Carlo Method
Radiotherapy Dosage
Journal of Biomedical Physics and Engineering

Articles in Press, Corrected Proof
Available Online from 20 July 2025

Home

Guide for Authors

Submit Manuscript

Guide for Reviewers

Contact Us